BACKGROUND:Genetic studies in yeast have identified class E vps genes that form the ESCRT complexes required for protein sorting at the early endosome.In Drosophila, mutations of the ESCRT-II Hiking Boots component vps25 cause endosomal defects leading to accumulation of Notch protein and increased Notch pathway activity.These endosomal and signali
The Skolem problem is a long-standing open problem in linear dynamical systems: can a linear recurrence sequence (LRS) ever reach 0 from a given initial configuration? Similarly, the positivity problem asks whether the LRS stays positive from an initial configuration.Deciding Skolem (or positivity) has been open for half a century: the best known d
Aim to improve the quality of life of patients in the early postoperative period Vice Wallet after septoplasty.Material and methods.The study involved patients who underwent septoplasty (n=51).The patients were divided into two groups: in group A (n=26) classic intranasal splints were installed at the end of the operation; in group B (n=25) we used